JAMA Pediatrics Current Issue http://www.elizeaboutbeauty.com/journals/jamapediatrics en-us Mon, 05 Apr 2021 00:00:00 GMT Mon, 05 Apr 2021 11:43:41 GMT Silverchair jamams@jamanetwork.org support@www.elizeaboutbeauty.com Umbilical Cord Management Strategies in Preterm Infants http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2776977 Mon, 05 Apr 2021 00:00:00 GMT Jasani B, Torgalkar R, Ye XY, et al. This systematic review and network meta-analysis compares 4 umbilical cord management strategies for preterm infants: immediate cord clamping, delayed cord clamping, umbilical cord milking, and umbilical cord milking and delayed umbilical cord clamping. 175 4 e210102 10.1001/jamapediatrics.2021.0102 2776977 Prenatal Repair and Physical Functioning Among Children With Myelomeningocele http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2776161 Mon, 05 Apr 2021 00:00:00 GMT Houtrow AJ, MacPherson C, Jackson-Coty J, et al. This secondary analysis of a randomized clinical trial investigates whether children who had prenatal repair of myelomeningocele have better physical mobility than those with postnatal repair. 175 4 e205674 10.1001/jamapediatrics.2020.5674 2776161 Long-term Outcomes of Children After Fetal Surgery for Spina Bifida http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2776155 Mon, 05 Apr 2021 00:00:00 GMT Meuli M, Moehrlen U. The study by Houtrow et al is an eagerly awaited new chapter of an intriguing story that began almost 70 years ago. 175 4 e205687 10.1001/jamapediatrics.2020.5687 2776155 JAMA Pediatrics http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2778036 Thu, 01 Apr 2021 00:00:00 GMT Vision: JAMA Pediatrics will be the most respected source of information for investigators, providers, and policy makers seeking the highest quality evidence to guide decision making. 175 4 339 339 10.1001/jamapediatrics.2020.4159 2778036 What Parents Need to Know About Teen Vaping and What They Can Do About It http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2776603 Thu, 01 Apr 2021 00:00:00 GMT Salloum RG, Tan AL, Thompson L. This Patient Page discusses how parents can identify whether teens are vaping, how to help prevent vaping, and what to do if their teen is addicted to vaping. 175 4 440 440 10.1001/jamapediatrics.2020.6689 2776603 Experimental Designs to Optimize Treatments for Individuals http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2776426 Thu, 01 Apr 2021 00:00:00 GMT Davidson KW, Silverstein M, Cheung K, et al. This Special Communication advocates the use of personalized N-of-1 trials in clinical settings as a means of identifying optimal treatment options for individual patients. 175 4 404 409 10.1001/jamapediatrics.2020.5801 2776426 Misspelled Author Name in the Byline http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2776420 Thu, 01 Apr 2021 00:00:00 GMT In the Editorial “Intrapartum Maternal Oxygen Supplementation—Friend or Foe?,?published online January 4, 2021, there was an error in the byline. The third author given as “Alireza A. Shamishirsaz, MD, ?should have appeared as “Alireza A. Shamshirsaz, MD.?This article has been corrected online. 175 4 435 435 10.1001/jamapediatrics.2021.0031 2776420 Association Between Proton Pump Inhibitor Use and Risk of Asthma in Children http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2776162 Thu, 01 Apr 2021 00:00:00 GMT Wang Y, Wintzell V, Ludvigsson JF, et al. This cohort study investigates the association between initiating use of proton pump inhibitors and the risk of asthma in children. 175 4 394 403 10.1001/jamapediatrics.2020.5710 2776162 Effect of Enteral Lipids on Severe Retinopathy of Prematurity http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775874 Thu, 01 Apr 2021 00:00:00 GMT Hellström A, Nilsson AK, Wackernagel D, et al. This randomized clinical trial examines whether enteral supplementation with arachidonic acid and docosahexaenoic acid from birth to 40 weeks?postmenstrual age reduces retinopathy of prematurity in extremely preterm infants. 175 4 359 367 10.1001/jamapediatrics.2020.5653 2775874 Effect of a Family Media Use Plan on Media Rule Engagement Among Adolescents http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775421 Thu, 01 Apr 2021 00:00:00 GMT Moreno MA, Binger KS, Zhao Q, et al. This randomized clinical trial examines the application and outcomes of a tool for monitoring and planning media or screen use in families with older children and adolescents. 175 4 351 358 10.1001/jamapediatrics.2020.5629 2775421 Population vs Individual Prediction of Poor Health From Adverse Childhood Experiences Screening http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775420 Thu, 01 Apr 2021 00:00:00 GMT Baldwin JR, Caspi A, Meehan AJ, et al. This cohort study uses data from 2 birth cohorts to test the predictive accuracy of adverse childhood experience screening for later health problems. 175 4 385 393 10.1001/jamapediatrics.2020.5602 2775420 Efficacy of 3 Major Ketogenic Diet Therapies in Children With Drug-Resistant Epilepsy—Reply http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775419 Thu, 01 Apr 2021 00:00:00 GMT Sondhi V, Gulati S. In Reply We thank Yue et al for their interest in our article and value the opportunity to clarify some aspects of our study. First, they raise concerns about the exclusion of surgically remediable epilepsy. We agree with Yue et al that using the ketogenic diet reduces seizure burden among children with surgically remediable epilepsy and can be used as a bridge to epilepsy surgery. However, the ketogenic diet in this scenario is palliative, and removing the epileptogenic focus is often curative. Hence, we excluded 4 children with surgically remediable epilepsy from our study, and they were offered curative surgery. These included focal heterotopia (n??) and mesial temporal sclerosis (n??). The same has also been highlighted in Figure 1 of our article. Thus, to reiterate, although the ketogenic diet can reduce seizure burden in surgically remediable epilepsy, surgery is the modality of choice for these children’s treatment. 175 4 434 435 10.1001/jamapediatrics.2020.5451 2775419 Prenatal Opioid Exposure and Motor Cortex Volume—Reply http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775418 Thu, 01 Apr 2021 00:00:00 GMT Hartwell ML, Croff JM. In Reply Our study, titled “Association of Prenatal Opioid Exposure With Precentral Gyrus Volume in Children,?is among the first to identify an association between prenatal prescription opioids exposure (RxPOE), which was understated in the original article, and the precentral gyrus, a part of the brain used to control motor function. Our hypothesis arose from earlier research noting delayed motor skills among children with RxPOE and studies of children with prenatal exposure to other opiates and drugs. Our retrospective, cross-sectional analysis, using data from more than 10?00 participants from the Adolescent Brain Cognitive Development study, shows that structural differences in this region of the motor cortex are discernable among children with RxPOE. Koren notes several studies involving methadone, buprenorphine, or illicit opioid use; however, none of the studies involved measures from magnetic resonance imaging or brain development. One study from the Appalachian region of Tennessee focused on neonatal abstinence syndrome and noted the differences in use patterns between the Appalachian region of Tennessee and the state as a whole. This study identified a use rate of 28.7% illicit opioids at the state level and a 36.2% use rate in the Appalachian region. Moreover, 58.0% of prescription opioid use in this region was for prescriptions not prescribed to the mother. These points differ from our study in that we compared structural components of the brain among children with and without RxPOE, not dependent on neonatal abstinence syndrome diagnosis or treatment. While our modeling holds to statistical parsimony, it is well informed and extends further in consideration of additional variables than what has been explored in previous, relevant studies involving magnetic resonance imaging data, and prenatal exposure to opiates. Our adjusted models controlled for prenatal exposures to alcohol and tobacco, arguably the most important known factors in fetal development, age, sex, race/ethnicity, and socioeconomic factors (financial risk and single-adult households) to account for the child’s social environment. While we did not explicitly state it as a limitation of the study, we did acknowledge that “analysis of other variables within the Adolescent Brain Cognitive Development study data set may elucidate the functional, cognitive, and behavioral results of these neuroanatomical differences,?and acknowledge there is potential for a future study to examine the stability of effects among the included variables and other covariates within this area of research, as well as the exploration of the collinearity between them. Further, because the nature of the study is associative, we made no mention of causality; however, given our findings, we recommend clinical screening for RxPOE during pregnancy, which should be included among other associated risk factors, such as a mother’s medical diagnoses, because our intention was and is to create the best possible outcomes for all children. 175 4 429 430 10.1001/jamapediatrics.2020.5332 2775418 Efficacy of 3 Major Ketogenic Diet Therapies in Children With Drug-Resistant Epilepsy http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775417 Thu, 01 Apr 2021 00:00:00 GMT Yue J, Liu S, Yang H. To the Editor We read with interest the Original Investigation “Efficacy of Ketogenic Diet, Modified Atkins Diet, and Low Glycemic Index Therapy Diet Among Children With Drug-Resistant Epilepsy: A Randomized Clinical Trial?by Sondhi et al, published in JAMA Pediatrics. The authors indicate that the modified Atkins diet and low glycemic index therapy diet are not noninferior to the classic ketogenic diet (KD) with respect to seizure reduction at 24 weeks after diet initiation among children with drug-resistant epilepsy. There are several concerns about this study. 175 4 434 434 10.1001/jamapediatrics.2020.5448 2775417 Prenatal Opioid Exposure and Motor Cortex Volume http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775416 Thu, 01 Apr 2021 00:00:00 GMT Koren G. To the Editor Hartwell et al published evidence, based on a very large cohort, that prenatal opioid exposure is negatively associated with the volume of motor cortex, which may explain neurodevelopmental deficits. By their nature, observational studies can document association but not causation. Any attempt to move toward causation must deal with identifying and adjusting for confounders that may affect the measured differences in motor cortex. Hartwell et al have attempted to adjust for differences between prenatal opioid users and controls by considering race/ethnicity, alcohol and tobacco exposure, measures of financial risks, and single-adult household, all of which are important confounders that may help separate the 2 comparison groups. However, mothers who use opioids in late pregnancy are very different in many other aspects that may affect offspring outcome, which were not adjusted for in the analysis. Here is a partial list of variables proven to cluster among mothers using opioid prenatally, which were not included in the Hartwell et al analysis and may affect neurologic outcome: 175 4 428 429 10.1001/jamapediatrics.2020.5317 2775416 Family Media Use Planning With Teens—Is It Time for Shared Decision-making? http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775414 Thu, 01 Apr 2021 00:00:00 GMT Kroshus E, Christakis D. Managing screen use in an ever-evolving media landscape is a challenge for many families, particularly families with adolescents. Whereas with younger children, parents can more readily restrict access to screens and monitor screen use, adolescents are often in situations without direct parental oversight. The heightened role of screens in adolescent socialization and schoolwork further complicates the use of media-related strategies that require a high degree of parental control. Moreover, and consistent with self-determination theory, highly controlling parenting may thwart emergent adolescent needs for autonomy, limit the development of intrinsic motivation, and lead to noncompliance with parent-desired behaviors. Autonomy-supportive parenting is distinct from permissive or uninvolved parenting in that it includes a developmentally appropriate amount of parental involvement, with the goal of fostering increasing independence and self-regulation. Evidence suggests that autonomy-supportive parent communication about media use is associated with less media use concealment by adolescents. In sum, parent-identified and enforced rules alone are likely not sufficient for adolescents to gain the buy-in necessary for consistent implementation of limits on media use and may constrain the development of important self-determined motivation and skills necessary for self-regulation in the transition to independent living (eg, college). 175 4 349 350 10.1001/jamapediatrics.2020.5637 2775414 Association of Cannabis Use With Self-harm and Mortality Risk Among Youths With Mood Disorders http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775255 Thu, 01 Apr 2021 00:00:00 GMT Fontanella CA, Steelesmith DL, Brock G, et al. This cohort study uses Medicaid data to examine associations of cannabis use disorder with self-harm, suicide, and overall mortality risk in youths with mood disorders. 175 4 377 384 10.1001/jamapediatrics.2020.5494 2775255 Nonintervention Is Not Noninferior to Oral Ibuprofen for Treatment of Patent Ductus Arteriosus—Reply http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775253 Thu, 01 Apr 2021 00:00:00 GMT Sung S, Lee M, Park W. In Reply We thank Razak for the comments on our randomized clinical trial comparing nonintervention and oral ibuprofen treatment for patent ductus arteriosus (PDA). 175 4 430 431 10.1001/jamapediatrics.2020.5329 2775253 Pros and Cons in Using Population-Based Registers for Assessing the Fetal Safety of Drugs—Reply http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775252 Thu, 01 Apr 2021 00:00:00 GMT Andersson N, Andersen J. In Reply We thank Triunfo et al for their interest in our article. They relevantly note that caution is warranted when drawing conclusions from registry-based studies owing to the limitations of observational designs, including the lack of randomization. With the view that randomized clinical trials are in general unlikely to be conducted within the field of drug safety in pregnancy, observational data provide means to help inform patients, clinicians, and drug regulatory agencies on this issue. In addition, while the relative rarity of both exposure and outcomes brings difficulties in performing studies of drug safety in pregnancy, the use of nationwide registry data allows the identification of a sufficient number of exposed pregnancies to reach adequate power. 175 4 427 428 10.1001/jamapediatrics.2020.5323 2775252 Nonintervention Is Not Noninferior to Oral Ibuprofen for Treatment of Patent Ductus Arteriosus http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775251 Thu, 01 Apr 2021 00:00:00 GMT Razak A. To the Editor This Letter highlights the flaws of a recent randomized clinical trial by Sung et al that concluded that nonintervention is noninferior to oral ibuprofen for patent ductus arteriosus (PDA) treatment in reducing death or bronchopulmonary dysplasia (BPD) in preterm infants. 175 4 430 430 10.1001/jamapediatrics.2020.5326 2775251 Pros and Cons in Using Population-Based Registers for Assessing the Fetal Safety of Drugs http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775250 Thu, 01 Apr 2021 00:00:00 GMT Triunfo S, Ceschi A. To the Editor Andersson et al investigate the risk of adverse fetal outcomes associated with the use of a second-generation antihistamine (fexofenadine) among 2962 pregnancies with fexofenadine use matched in a 1:1 ratio with those with the use of the currently recommended second-generation antihistamines (cetirizine). No association has been noted between fexofenadine use during pregnancy and increased risk of major birth defects, spontaneous, preterm birth, and stillbirth. 175 4 427 427 10.1001/jamapediatrics.2020.5314 2775250 Why Is Antibiotic Treatment Rarely Performed in COVID-19–Positive Children Admitted in Pediatric Intensive Care Units?—Reply http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775014 Thu, 01 Apr 2021 00:00:00 GMT Shekerdemian LS, Burns JP. In Reply We thank Fanos and colleagues for their comments regarding our article and specifically referring to the lack of antibiotic use in our cohort of pediatric patients hospitalized with coronavirus disease 2019 (COVID-19). While they correctly state that alterations in gut permeability and subsequent disturbances in the pulmonary microbiome may contribute to severity of lung injury in patients with acute respiratory distress syndrome, we would like to point out that they may have misinterpreted the specific aims of our investigation. 175 4 432 432 10.1001/jamapediatrics.2020.5360 2775014 Maternal Elimination Diet and Symptoms of Cow’s Milk Allergy in Breastfed Infants—Reply http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775013 Thu, 01 Apr 2021 00:00:00 GMT Munblit D, Palmer DJ, Boyle RJ. In Reply We thank Hilvo for commenting on our article and highlighting studies from the 1980s that reported infant responses to maternal dietary exclusions. In fact, there is a longer history of this concept that a breastfeeding woman’s dietary intake may cause allergic reactions in her infant, with the first report of infant “allergic?response to maternal intake of chocolate published in 1918. However, as Hilvo rightly points out, and Cochrane reviews have also identified, randomized clinical trial evidence in this field is inconsistent. Case reports, observational studies, and personal and clinical experience support the existence of infants whose symptoms respond to maternal dietary intake. But this phenomenon occurs in both allergic and nonallergic infants. 175 4 426 427 10.1001/jamapediatrics.2020.5320 2775013 Why Is Antibiotic Treatment Rarely Performed in COVID-19–Positive Children Admitted in Pediatric Intensive Care Units? http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775011 Thu, 01 Apr 2021 00:00:00 GMT Fanos V, Bardanzellu F, Marcialis M. To the Editor Shekerdemian et al reported 48 coronavirus disease 2019–positive children (median age, 13 years) admitted to pediatric intensive care units in the US and Canada. Overall, 83% of children were not treated with antibiotics, and 17% had been treated with azithromycin. We deeply reflected on this, especially considering that 83% were also affected by severe comorbidities. 175 4 431 432 10.1001/jamapediatrics.2020.5348 2775011 Maternal Elimination Diet and Symptoms of Cow’s Milk Allergy in Breastfed Infants http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775010 Thu, 01 Apr 2021 00:00:00 GMT Hilvo M. To the Editor The Special Communication by Munblit et al, “Assessment of Evidence About Common Infant Symptoms and Cow’s Milk Allergy,?concluded that recommendations to manage common infant symptoms as cow’s milk allergy (CMA) are not evidence based, especially in breastfed infants who are not directly consuming cow’s milk. Analysis of the authors suggested that for more than 99% of the infants with proven CMA, breast milk from a cow’s milk–consuming mother contains insufficient β-lactoglobulin levels to trigger an allergic reaction. Although the authors admitted limitations in their analysis, it should be furthermore noted that the analysis was based on indirect evidence; it compares thresholds of proteins needed to induce allergic reaction in older children than breast-fed infants with the concentration of a single cow’s milk component in breast milk. In fact, this is not evidence based, and one should look at more direct evidence. 175 4 425 426 10.1001/jamapediatrics.2020.5311 2775010 Trends in Pediatric Hospitalizations for Coronavirus Disease 2019 http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775008 Thu, 01 Apr 2021 00:00:00 GMT Levin Z, Choyke K, Georgiou A, et al. This study examines coronavirus disease 2019 hospitalization trends for pediatric patients in 22 states. 175 4 415 417 10.1001/jamapediatrics.2020.5535 2775008 Assessment of Immunization Requirements, Policies, and Practices in a National Cohort of Summer Camps http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2775007 Thu, 01 Apr 2021 00:00:00 GMT Bunke C, Schellpfeffer N, Garst B, et al. This study surveys a national cohort of summer camp leadership to assess camps?immunization requirements, policies, and practices. 175 4 421 423 10.1001/jamapediatrics.2020.5342 2775007 Maternal Oxygen Supplementation Compared With Room Air for Intrauterine Resuscitation http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2774699 Thu, 01 Apr 2021 00:00:00 GMT Raghuraman N, Temming LA, Doering MM, et al. This systematic review and meta-analysis examines randomized clinical trials on the use of oxygen vs room air in women in labor or undergoing cesarean delivery. 175 4 368 376 10.1001/jamapediatrics.2020.5351 2774699 Rapid Implementation of Model-Based Dosing Recommendations During the Coronavirus Disease 2019 Pandemic—Reply http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2774698 Thu, 01 Apr 2021 00:00:00 GMT Maharaj AR, Hornik CP, Cohen-Wolkowiez M. In Reply We would like to thank de Wildt and colleagues for their thoughtful commentary pertaining to our recently published article. We agree with the authors, who stressed the importance of translating these model-based dosing regimens toward clinical practice. Additionally, we would like to highlight the critical urgency for prospective randomized clinical trials evaluating the pharmacokinetics, safety, and efficacy of investigational treatments for coronavirus disease 2019 (COVID-19) in children. Such clinical investigations are essential to bridge the gap between simulation-based analyses and clinical practice. 175 4 433 433 10.1001/jamapediatrics.2020.5398 2774698 Ways to Support Low-Income, At-Risk Young Children During and After Coronavirus Disease 2019—Reply http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2774697 Thu, 01 Apr 2021 00:00:00 GMT Dooley DG, Bandealy A, Tschudy MM. In Reply In our article published in May 2020, we highlighted the need for innovative ways of delivering education, health, and social services owing to the disruptions caused by the coronavirus disease 2019 COVID-19 pandemic. As the the pandemic progresses, many school districts have implemented virtual learning during the fall semester. We appreciate Wong’s identification of a novel way to deliver preschool and early intervention services to children and directly engage parents through employment. Training parents to deliver services could help overcome the challenges that young children face with the virtual learning environment, including attention span, curricular content, and the need for parent supervision even if content is available online. One factor to consider with respect to this approach would be that students would miss the in-person interaction and socialization with their peers that occurs in a classroom setting that can also be beneficial for development. 175 4 425 425 10.1001/jamapediatrics.2020.5287 2774697 Rapid Implementation of Model-Based Dosing Recommendations During the Coronavirus Disease 2019 Pandemic http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2774696 Thu, 01 Apr 2021 00:00:00 GMT de Wildt SN, Verscheijden LM, van der Zanden TM. To the Editor With great interest, we read the article by Maharaj et al and the accompanying Editorial by Watt. We can only applaud the authors, the Pediatric Trial Network, and the journal for showing the pediatric community the added value of modeling and simulation in situations where pediatric data are scarce. We would like to take the opportunity to stress the importance of translating these model-based dosing guidelines to clinical care. Most pediatricians are not familiar with pharmacokinetic articles and may be hesitant to use simulated doses from scientific publications in real-life clinic. 175 4 432 433 10.1001/jamapediatrics.2020.5395 2774696 Children With Disabilities Must Be More Than an Afterthought in School Reopening http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2774695 Thu, 01 Apr 2021 00:00:00 GMT Sholas MG, Apkon SD, Houtrow AJ. To the Editor The Individuals With Disabilities Education Act, adopted in 1975, mandates that all children have a right to appropriate and free public education services. Fourteen percent of public school enrollees (7.1 million children) receive special education services. Many children served by the Individuals With Disabilities Education Act are at high risk for severe illness if they contract coronavirus disease 2019. Thus, the US Centers for Disease Control and Prevention identifies this group for special consideration when reopening schools. A JAMA Pediatrics Editorial correctly asserted that issues related to school reopening were not getting adequate attention. A critical part of this planning is being proactive for children with disabilities. 175 4 423 424 10.1001/jamapediatrics.2020.5308 2774695 Ways to Support Low-Income, At-Risk Young Children During and After Coronavirus Disease 2019 http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2774694 Thu, 01 Apr 2021 00:00:00 GMT Wong V. To the Editor In an issue of JAMA Pediatrics, Dooley et al bring up the important issue of supporting low-income children during coronavirus disease 2019 (COVID-19) and suggest that US Congress should increase investments in evidence-based programs (eg, home visiting and Head Start) and digital learning. Expanding evidence-based programs in the early intervention (EI) and preschool school systems may be more challenging than we thought, even before COVID-19. For instance, approximately 170?00 low–socioeconomic status (SES) children aged 3 or 4 years who were eligible for state-run preschools in California were not enrolled in state-run preschools. Governor Newsom wanted to expand 10?00 preschool spots after he took office but unfortunately did not, in part because of limited school facility capacities and teacher shortage. As a result, a large fraction of $100 million of education funds remain unused. 175 4 424 425 10.1001/jamapediatrics.2020.5284 2774694 Translation of a Host Blood RNA Signature Distinguishing Bacterial From Viral Infection Into a a Point-of-Care Test http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2774693 Thu, 01 Apr 2021 00:00:00 GMT Pennisi I, Rodriguez-Manzano J, Moniri A, et al. This study assesses a 2-gene RNA signature that can be translated into a rapid (<25 minutes) and portable laboratory-on-a-chip platform suitable for development as a point-of-care test. 175 4 417 419 10.1001/jamapediatrics.2020.5227 2774693 Obesity and Eating Disorder Disparities Among Sexual and Gender Minority Youth http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2773982 Thu, 01 Apr 2021 00:00:00 GMT Schvey NA, Pearlman AT, Klein DA, et al. This study assesses obesity, binge eating disorder, anorexia nervosa, and bulimia nervosa among sexual and gender minority children. 175 4 412 415 10.1001/jamapediatrics.2020.5152 2773982 Solitary Use of Alcohol and Marijuana by US 12th Grade Students, 1976-2019 http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2773794 Thu, 01 Apr 2021 00:00:00 GMT Terry-McElrath YM, O’Malley PM, Patrick ME. This cohort study examines changes in the rates of solitary alcohol and marijuana use among 12th grade students between 1976 and 2019. 175 4 419 421 10.1001/jamapediatrics.2020.5211 2773794 Using Metrics of Kg (or Lb) Overweight or Obese to Help Interpret and Communicate Magnitudes of Excess Body Mass Index http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2773793 Thu, 01 Apr 2021 00:00:00 GMT Robinson TN. This study uses weight data from a cohort of children aged 7 to 11 years to assess a new method of communicating about body mass index, overweight, and obesity with patients and their families. 175 4 410 412 10.1001/jamapediatrics.2020.5196 2773793 Allocating Resources Across the Life Span During COVID-19 http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2773515 Thu, 01 Apr 2021 00:00:00 GMT Lemmon ME, Truog RD, Ubel PA. This Viewpoint discusses the need to account for neonates and children—who are typically disproportionally impacted during pandemics—by implementing hospital resource allocation protocols that ensure equity across the life span. 175 4 347 348 10.1001/jamapediatrics.2020.5215 2773515 COVID-19 Pandemic Health Disparities and Pediatric Health Care http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2773313 Thu, 01 Apr 2021 00:00:00 GMT Menon DU, Belcher HE. This Viewpoint examines the association between the COVID-19 pandemic and how the changes to telehealth are helping close the gap between clinicians and pediatric physical and mental health care patients. 175 4 345 346 10.1001/jamapediatrics.2020.5097 2773313 The Complicated Legacy of Cassandra Callender http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2773005 Thu, 01 Apr 2021 00:00:00 GMT Marron JM, Meyer EC, Kennedy KO. This Viewpoint discusses the role of adolescents in decisions about their health care, particularly potentially life-saving interventions. 175 4 343 344 10.1001/jamapediatrics.2020.4812 2773005 Intervention Recommendations for Children With Autism in Light of a Changing Evidence Base http://www.elizeaboutbeauty.com/journals/jamapediatrics/fullarticle/2772825 Thu, 01 Apr 2021 00:00:00 GMT Sandbank M, Bottema-Beutel K, Woynaroski T. This Viewpoint summarizes the authors?previous findings that a greater intensity of behavioral interventions in children with autism showed no association with increased benefits. 175 4 341 342 10.1001/jamapediatrics.2020.4730 2772825 4887王中王鉄算 盘开奖结果小说