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          Year

          Day

          November 19, 2020
          Original Investigation

          Insights From Survival Analyses During 12 Years of Anti–Vascular Endothelial Growth Factor Therapy for Neovascular Age-Related Macular Degeneration

          Abstract Full Text
          JAMA Ophthalmol. Published online November 19, 2020. doi:10.1001/jamaophthalmol.2020.5044

          This cohort study uses data from a tertiary eye center to assess the potential usefulness of survival analyses of 12 years of anti–vascular endothelial growth factor therapy for neovascular age-related macular degeneration.

          Efficacy and Safety of a Proposed Ranibizumab Biosimilar Product vs a Reference Ranibizumab Product for Patients With Neovascular Age-Related Macular Degeneration: A Randomized Clinical Trial

          Abstract Full Text
          open access
          JAMA Ophthalmol. Published online November 19, 2020. doi:10.1001/jamaophthalmol.2020.5053

          This randomized clinical trial compares the efficacy, safety, and immunogenicity of SB11, a ranibizumab biosimilar product, with that of the reference ranibizumab for patients with neovascular age-related macular degeneration (AMD).

          Brief Report

          Eye Protection for Patients With COVID-19 Undergoing Prolonged Prone-Position Ventilation

          Abstract Full Text
          free access
          JAMA Ophthalmol. Published online November 19, 2020. doi:10.1001/jamaophthalmol.2020.4988

          This case series describes 2 patients with coronavirus disease 2019 and orbital compartment syndrome, optic disc edema, and retinal hemorrhage in the setting of prolonged prone positioning in the intensive care unit.

          Special Communication

          Development, Validation, and Innovation in Ophthalmic Laser-Based Imaging: Report From a US Food and Drug Administration–Cosponsored Forum

          Abstract Full Text
          JAMA Ophthalmol. Published online November 19, 2020. doi:10.1001/jamaophthalmol.2020.4994

          This Special Communication describes a forum of laser-based imaging cosponsored by the US Food and Drug Administration and 11 professional ophthalmic, vision science, and optometric societies.

          JAMA Ophthalmology Clinical Challenge

          Persistent Red Eye Unresponsive to Topical Treatment

          Abstract Full Text
          has active quiz
          JAMA Ophthalmol. Published online November 19, 2020. doi:10.1001/jamaophthalmol.2020.4062

          A 68-year-old woman has a 3-week history of progressive eye redness and discomfort unresponsive to topical treatment. What would you do next?

          November 12, 2020
          Original Investigation

          Diagnostic Test Accuracy of the Red Reflex Test for Ocular Pathology in Infants: A Meta-analysis

          Abstract Full Text
          JAMA Ophthalmol. Published online November 12, 2020. doi:10.1001/jamaophthalmol.2020.4854

          This systematic review and meta-analysis reviews the literature on diagnostic accuracy of the red reflex test in infant screening for ocular pathologies and provides summary estimates of sensitivity and specificity.

          Association of Retinal Vascular Occlusion With Women Filling a Prescription for Female Hormone Therapy

          Abstract Full Text
          JAMA Ophthalmol. Published online November 12, 2020. doi:10.1001/jamaophthalmol.2020.4884

          This study investigates whether filling a prescription of female hormone therapy (FHT) is associated with an increased risk of retinal artery occlusion (RAO) or retinal vein occlusions (RVO).

          Retinal Imaging Findings in Carriers With PSEN1-Associated Early-Onset Familial Alzheimer Disease Before Onset of Cognitive Symptoms

          Abstract Full Text
          JAMA Ophthalmol. Published online November 12, 2020. doi:10.1001/jamaophthalmol.2020.4909

          This cross-sectional imaging study evaluates whether optical coherence tomography can detect early retinal alterations in carriers of the presenilin 1 (PSEN1) E280A mutation who are cognitively unimpaired.

          Brief Report

          Ocular Lesions Other Than Stings Following Yellow-Legged Hornet (Vespa velutina nigrithorax) Projections, as Reported to French Poison Control Centers

          Abstract Full Text
          JAMA Ophthalmol. Published online November 12, 2020. doi:10.1001/jamaophthalmol.2020.4877

          This case series describes ocular lesions occurring after exposure to a liquid projection emitted by a hornet (excluding stings in the eye).

          Invited Commentary

          The Enduring Value of Newborn Red Reflex Testing as a Screening Tool

          Abstract Full Text
          JAMA Ophthalmol. Published online November 12, 2020. doi:10.1001/jamaophthalmol.2020.4853
          JAMA Ophthalmology Clinical Challenge

          Progressive Eyelid Swelling in a Middle-aged Man

          Abstract Full Text
          has active quiz
          JAMA Ophthalmol. Published online November 12, 2020. doi:10.1001/jamaophthalmol.2020.4092

          A man in his 40s presents with a recent history of pain and swelling over his right orbit and upper eyelid, and computed tomography shows a right supraorbital abscess with mass effect. What would you do next?

          November 5, 2020
          Original Investigation

          Intense Simulation-Based Surgical Education for Manual Small-Incision Cataract Surgery: The Ophthalmic Learning and Improvement Initiative in Cataract Surgery Randomized Clinical Trial in Kenya, Tanzania, Uganda, and Zimbabwe

          Abstract Full Text
          open access
          JAMA Ophthalmol. Published online November 5, 2020. doi:10.1001/jamaophthalmol.2020.4718

          This randomized clinical trial examines whether adding simulation-based cataract surgical training to conventional training results in improved acquisition of surgical skills among trainees.

          Incidence of Drug Use–Related Endogenous Endophthalmitis Hospitalizations in the United States, 2003 to 2016

          Abstract Full Text
          JAMA Ophthalmol. Published online November 5, 2020. doi:10.1001/jamaophthalmol.2020.4741

          This study investigates changing trends in epidemiology, risk factors, hospital course, and costs associated with drug use–related endogenous endophthalmitis hospitalizations in the United States from 2003 to 2016.

          Association of Patterns of Glaucomatous Macular Damage With Contrast Sensitivity and Facial Recognition in Patients With Glaucoma

          Abstract Full Text
          JAMA Ophthalmol. Published online November 5, 2020. doi:10.1001/jamaophthalmol.2020.4749

          This cohort study evaluates the association of pattern of glaucomatous macular damage with contrast sensitivity and facial recognition among patients with glaucoma.

          Invited Commentary

          Redesigning Surgical Training Curriculum With Simulation: Lessons From the OLIMPICS Trial

          Abstract Full Text
          JAMA Ophthalmol. Published online November 5, 2020. doi:10.1001/jamaophthalmol.2020.4716
          JAMA Ophthalmology Clinical Challenge

          Recurrent Subconjunctival Hemorrhage in a Child With an Orbital Mass

          Abstract Full Text
          has active quiz
          JAMA Ophthalmol. Published online November 5, 2020. doi:10.1001/jamaophthalmol.2020.4087

          A 14-month-old girl presents with recurrent left subconjunctival hemorrhage with increasing frequency in the past 7 months, with a large inferior orbital lesion measuring more than 17 mm shown during B-scan examination. What would you do next?

          Comment & Response

          Studies of Microsurgical Skill—The Key Lies in the Design

          Abstract Full Text
          JAMA Ophthalmol. Published online November 5, 2020. doi:10.1001/jamaophthalmol.2020.4755

          Studies of Microsurgical Skill—The Key Lies in the Design—Reply

          Abstract Full Text
          JAMA Ophthalmol. Published online November 5, 2020. doi:10.1001/jamaophthalmol.2020.4758
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