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This cohort study uses data from a tertiary eye center to assess the potential usefulness of survival analyses of 12 years of anti–vascular endothelial growth factor therapy for neovascular age-related macular degeneration.

This randomized clinical trial compares the efficacy, safety, and immunogenicity of SB11, a ranibizumab biosimilar product, with that of the reference ranibizumab for patients with neovascular age-related macular degeneration (AMD).

This case series describes 2 patients with coronavirus disease 2019 and orbital compartment syndrome, optic disc edema, and retinal hemorrhage in the setting of prolonged prone positioning in the intensive care unit.

This Special Communication describes a forum of laser-based imaging cosponsored by the US Food and Drug Administration and 11 professional ophthalmic, vision science, and optometric societies.

A 68-year-old woman has a 3-week history of progressive eye redness and discomfort unresponsive to topical treatment. What would you do next?

This systematic review and meta-analysis reviews the literature on diagnostic accuracy of the red reflex test in infant screening for ocular pathologies and provides summary estimates of sensitivity and specificity.

This study investigates whether filling a prescription of female hormone therapy (FHT) is associated with an increased risk of retinal artery occlusion (RAO) or retinal vein occlusions (RVO).

This cross-sectional imaging study evaluates whether optical coherence tomography can detect early retinal alterations in carriers of the presenilin 1 (PSEN1) E280A mutation who are cognitively unimpaired.

This case series describes ocular lesions occurring after exposure to a liquid projection emitted by a hornet (excluding stings in the eye).

A man in his 40s presents with a recent history of pain and swelling over his right orbit and upper eyelid, and computed tomography shows a right supraorbital abscess with mass effect. What would you do next?

This randomized clinical trial examines whether adding simulation-based cataract surgical training to conventional training results in improved acquisition of surgical skills among trainees.

This study investigates changing trends in epidemiology, risk factors, hospital course, and costs associated with drug use–related endogenous endophthalmitis hospitalizations in the United States from 2003 to 2016.

This cohort study evaluates the association of pattern of glaucomatous macular damage with contrast sensitivity and facial recognition among patients with glaucoma.

A 14-month-old girl presents with recurrent left subconjunctival hemorrhage with increasing frequency in the past 7 months, with a large inferior orbital lesion measuring more than 17 mm shown during B-scan examination. What would you do next?