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          Year

          Day

          October 26, 2020
          Original Investigation

          Assessment of Emergency Department and Inpatient Use and Costs in Adult and Pediatric Functional Neurological Disorders

          Abstract Full Text
          has audio
          JAMA Neurol. Published online October 26, 2020. doi:10.1001/jamaneurol.2020.3753

          This economic evaluation assesses US emergency department and inpatient use and charges for functional neurological disorders.

          Special Communication

          Autologous Hematopoietic Stem Cell Transplant in Multiple Sclerosis: Recommendations of the National Multiple Sclerosis Society

          Abstract Full Text
          JAMA Neurol. Published online October 26, 2020. doi:10.1001/jamaneurol.2020.4025

          This narrative review describes autologous hematopoietic stem cell transplant for multiple sclerosis, including recent developments, emerging guidelines for usage, and pending investigations.

          October 19, 2020
          Editorial

          Cerebral Microbleeds and Antithrombotic Treatments—Stop Worrying About Bleeding

          Abstract Full Text
          JAMA Neurol. Published online October 19, 2020. doi:10.1001/jamaneurol.2020.3847
          Original Investigation

          Microbleeds and the Effect of Anticoagulation in Patients With Embolic Stroke of Undetermined Source: An Exploratory Analysis of the NAVIGATE ESUS Randomized Clinical Trial

          Abstract Full Text
          JAMA Neurol. Published online October 19, 2020. doi:10.1001/jamaneurol.2020.3836

          This prespecified analysis of a randomized clinical trial investigates the effect of cerebral microbleeds on patients with embolic stroke of undetermined source taking either daily rivaroxaban or aspirin.

          Association of Initial β-Amyloid Levels With Subsequent Flortaucipir Positron Emission Tomography Changes in Persons Without Cognitive Impairment

          Abstract Full Text
          JAMA Neurol. Published online October 19, 2020. doi:10.1001/jamaneurol.2020.3921

          This cohort study investigates the association between β-amyloid in positron emission tomography and subsequent tau accumulation in persons who were cognitively unimpaired, to gain insight into the temporal associations between β-amyloid and tau accumulation.

          Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis

          Abstract Full Text
          JAMA Neurol. Published online October 19, 2020. doi:10.1001/jamaneurol.2020.3536

          This genome-wide association study identifies additional Alzheimer disease risk loci in African American individuals using the African Genome Resource panel.

          Images in Neurology

          Creutzfeldt-Jakob Disease as a Novel Cause of Wing-Beating Tremor

          Abstract Full Text
          has multimedia
          JAMA Neurol. Published online October 19, 2020. doi:10.1001/jamaneurol.2020.3899

          This case report describes a man with Creutzfeldt-Jakob disease that involved a rare type of tremor.

          Correction

          Correction to Author’s Academic Degrees

          Abstract Full Text
          free access
          JAMA Neurol. Published online October 19, 2020. doi:10.1001/jamaneurol.2020.4087
          October 12, 2020
          Original Investigation

          Surgical Decompression for Space-Occupying Hemispheric Infarction: A Systematic Review and Individual Patient Meta-analysis of Randomized Clinical Trials

          Abstract Full Text
          JAMA Neurol. Published online October 12, 2020. doi:10.1001/jamaneurol.2020.3745

          This systematic review and individual patient meta-analysis of randomized clinical trials compares surgical decompression with medical care for space-occupying hemispheric infarction and whether patient characteristics are associated with treatment outcomes.

          Association Between Apolipoprotein E ε2 vs ε4, Age, and β-Amyloid in Adults Without Cognitive Impairment

          Abstract Full Text
          JAMA Neurol. Published online October 12, 2020. doi:10.1001/jamaneurol.2020.3780

          This cross-sectional study used screening data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer Disease Study (A4 Study) to assess whether the presence of the apolipoprotein E ε2 allele is protective against β-amyloid accumulation in the presence of ε4 in individuals without cognitive impairment.

          A 5-Decade Analysis of Incidence Trends of Ischemic Stroke After Transient Ischemic Attack: A Systematic Review and Meta-analysis

          Abstract Full Text
          JAMA Neurol. Published online October 12, 2020. doi:10.1001/jamaneurol.2020.3627

          This systematic review and meta-analysis calculates the pooled event rate for ischemic stroke within 2, 7, 30, and 90 days of a transient ischemic attack and compares this incidence among patients recruited before 1999, from 1999 to 2007, and after 2007.

          Images in Neurology

          Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy With the Detection of Anti-GM3 and Anti-GM4 IgG Antibodies, Masquerading as Brown-Sequared Syndrome

          Abstract Full Text
          JAMA Neurol. Published online October 12, 2020. doi:10.1001/jamaneurol.2020.3828

          This article describes a woman with a disease that was initially diagnosed as Brown-Sequared syndrome but later shown to be glial fibrillary acidic protein astrocytopathy involving anti-GM3 and anti-GM4 IgG antibodies.

          October 5, 2020
          Research Letter

          Biotinidase Deficiency as a Mimic of Neuromyelitis Optica Spectrum Disorder in Childhood

          Abstract Full Text
          JAMA Neurol. Published online October 5, 2020. doi:10.1001/jamaneurol.2020.3558

          This study details a case of biotinidase deficiency mimicking neuromyelitis optica spectrum disorders and reviews prior cases of biotinidase deficiency that met Wingerchuck 2015 criteria for neuromyelitis optica spectrum disorder.

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