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          Year

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          November 16, 2020
          Images in Neurology

          Hyperacute Spontaneous Intracerebral Hemorrhage During Computed Tomography Scanning

          Abstract Full Text
          JAMA Neurol. Published online November 16, 2020. doi:10.1001/jamaneurol.2020.4355

          This case report describes a man who experienced a hyperacute spontaneous intracerebral hemorrhage when a computed tomography scan was underway.

          JAMA Neurology Clinical Challenge

          A Middle-Aged Woman With Severe Scoliosis and Encephalopathy

          Abstract Full Text
          has active quiz has multimedia
          JAMA Neurol. Published online November 16, 2020. doi:10.1001/jamaneurol.2020.4270

          A 42-year-old woman presented with clinical features of microcephaly, short stature, intellectual disability, severe degree of scoliosis, gait abnormality, and encephalopathy. What is your diagnosis?

          November 9, 2020
          Viewpoint

          Reforming the Process for Deep Brain Stimulation and Neurologic Device Approval in Rare Diseases

          Abstract Full Text
          JAMA Neurol. Published online November 9, 2020. doi:10.1001/jamaneurol.2020.4232

          This Viewpoint posits that the regnant approval process for the use of neurotechnological devices to treat rare diseases is in need of reform.

          Editorial

          Rapid Progress Toward Reliable Blood Tests for Alzheimer Disease

          Abstract Full Text
          JAMA Neurol. Published online November 9, 2020. doi:10.1001/jamaneurol.2020.4200
          Original Investigation

          Associations of Plasma Phospho-Tau217 Levels With Tau Positron Emission Tomography in Early Alzheimer Disease

          Abstract Full Text
          open access
          JAMA Neurol. Published online November 9, 2020. doi:10.1001/jamaneurol.2020.4201

          This cohort study compares plasma levels of phosphorylated tau at threonine 217 with established cerebrospinal fluid and positron emission tomography (PET) tau biomarkers in early Alzheimer disease.

          Comment & Response

          Air Pollution, Cardiovascular Disease, and Dementia

          Abstract Full Text
          JAMA Neurol. Published online November 9, 2020. doi:10.1001/jamaneurol.2020.4297

          Air Pollution, Cardiovascular Disease, and Dementia

          Abstract Full Text
          JAMA Neurol. Published online November 9, 2020. doi:10.1001/jamaneurol.2020.4309

          Air Pollution, Cardiovascular Disease, and Dementia—Reply

          Abstract Full Text
          JAMA Neurol. Published online November 9, 2020. doi:10.1001/jamaneurol.2020.4312
          November 7, 2020
          Original Investigation

          Ticagrelor Added to Aspirin in Acute Ischemic Stroke or Transient Ischemic Attack in Prevention of Disabling Stroke: A Randomized Clinical Trial

          Abstract Full Text
          open access
          JAMA Neurol. Published online November 7, 2020. doi:10.1001/jamaneurol.2020.4396

          This randomized clinical trial evaluates the superiority of ticagrelor added to aspirin in preventing disabling stroke and identifies factors associated with recurrent disabling stroke.

          November 2, 2020
          Original Investigation

          Burden of Neurological Disorders Across the US From 1990-2017: A Global Burden of Disease Study

          Abstract Full Text
          open access
          JAMA Neurol. Published online November 2, 2020. doi:10.1001/jamaneurol.2020.4152

          This analysis of the Global Burden of Disease 2017 study presents burden estimates of major neurological disorders in the US states by age and sex from 1990 to 2017.

          Brief Report

          Association of Reperfusion After Thrombolysis With Clinical Outcome Across the 4.5- to 9-Hours and Wake-Up Stroke Time Window: A Meta-Analysis of the EXTEND and EPITHET Randomized Clinical Trials

          Abstract Full Text
          JAMA Neurol. Published online November 2, 2020. doi:10.1001/jamaneurol.2020.4123

          This meta-analysis of 2 randomized clinical trials examines the association of reperfusion and reduced disability, including by onset-to-randomization time strata.

          Images in Neurology

          Combined Cranial Intraosseous and Cerebral Cavernous Malformations With Pathogenic CCM1 Germline Sequence Variations

          Abstract Full Text
          JAMA Neurol. Published online November 2, 2020. doi:10.1001/jamaneurol.2020.4134

          This case report describes cerebral cavernous malformations detected by susceptibility-weighted imaging and associated with a CCM1 sequence variation.

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