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          November 2020, Vol 3, No. 11

          IMAGING

          Trends in Imaging for Suspected Pulmonary Embolism Across US Health Care Systems, 2004 to 2016

          This cohort study assesses the use of advanced imaging tests, including chest computed tomography, computed tomographic pulmonary angiography, and ventilation-perfusion scan, for pulmonary embolism from 2004 to 2016.

          open access
          JAMA Netw Open. 2020;3(11):e2026930. doi:10.1001/jamanetworkopen.2020.26930
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Connectivity of the Cerebello-Thalamo-Cortical Pathway in Survivors of Childhood Leukemia Treated With Chemotherapy Only

          This cross-sectional study examines associations among brain volume, brain network connectivity, and neurocognitive test performance in survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only.

          open access
          JAMA Netw Open. 2020;3(11):e2025839. doi:10.1001/jamanetworkopen.2020.25839
          Abstract Full Text pdf link PDF
          CARDIOLOGY

          Assessment of Trends in Statin Therapy for Secondary Prevention of Atherosclerotic Cardiovascular Disease in US Adults From 2007 to 2016

          This cohort study assesses 10-year use, adherence, cost, and outcome trends in statin therapy for atherosclerotic cardiovascular disease in US adults using nationwide research center database information.

          open access
          JAMA Netw Open. 2020;3(11):e2025505. doi:10.1001/jamanetworkopen.2020.25505
          Abstract Full Text pdf link PDF
          RESEARCH LETTER SURGERY

          Evaluation of Electric Scooter Head and Neck Injuries in Paris, 2017-2019

          This case series study evaluates head and neck injuries caused by electric scooters in Paris, 2017-2019, focusing on user behavior and injury types.

          open access
          JAMA Netw Open. 2020;3(11):e2026698. doi:10.1001/jamanetworkopen.2020.26698
          Abstract Full Text pdf link PDF
          CORRECTION

          Errors in Text

          open access
          JAMA Netw Open. 2020;3(11):e2029099. doi:10.1001/jamanetworkopen.2020.29099
          Abstract Full Text pdf link PDF
          SURGERY

          Association of Circulating Tumor DNA With Disease-Free Survival in Breast Cancer: A Systematic Review and Meta-analysis

          This systematic review and meta-analysis uses data from studies retrieved from a Cochrane Library, ScienceDirect, PubMed, and Embase search to investigate the association of circulating tumor DNA with disease-free survival in patients with breast cancer.

          open access
          JAMA Netw Open. 2020;3(11):e2026921. doi:10.1001/jamanetworkopen.2020.26921
          Abstract Full Text pdf link PDF
          SURGERY

          Association of Hospital-Level Intensive Care Unit Use and Outcomes in Older Patients With Isolated Rib Fractures

          This cohort study characterizes interhospital variability in intensive care unit vs non–intensive care unit admission of older patients with isolated rib fractures and evaluates whether greater hospital-level use of intensive care units is associated with improved outcomes.

          open access
          JAMA Netw Open. 2020;3(11):e2026500. doi:10.1001/jamanetworkopen.2020.26500
          Abstract Full Text pdf link PDF
          GERIATRICS

          Assessment of Leisure Time Physical Activity and Brain Health in a Multiethnic Cohort of Older Adults

          This cross-sectional study examines the association between leisure time physical activity and measures of brain health assessed by magnetic resonance imaging in older adults.

          open access
          JAMA Netw Open. 2020;3(11):e2026506. doi:10.1001/jamanetworkopen.2020.26506
          Abstract Full Text pdf link PDF
          NUTRITION, OBESITY, AND EXERCISE

          Association of the Mediterranean Diet With Onset of Diabetes in the Women’s Health Study

          This cohort study characterizes the relative association of conventional and novel biomarkers in Mediterranean diet–related type 2 diabetes risk reduction in a US population.

          open access
          JAMA Netw Open. 2020;3(11):e2025466. doi:10.1001/jamanetworkopen.2020.25466
          Abstract Full Text pdf link PDF
          GERIATRICS

          Association Between Wearable Device–Based Measures of Physical Frailty and Major Adverse Events Following Lower Extremity Revascularization

          This cohort study tests a frailty meter that does not rely on gait to determine the risk of 30-day major adverse events among patients with chronic limb-threatening ischemia who have undergone lower extremity revascularization.

          open access
          JAMA Netw Open. 2020;3(11):e2020161. doi:10.1001/jamanetworkopen.2020.20161
          Abstract Full Text pdf link PDF
          OBSTETRICS AND GYNECOLOGY

          Pregnancy Outcomes Among Women With and Without Severe Acute Respiratory Syndrome Coronavirus 2 Infection

          This cohort study evaluates the adverse outcomes associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among pregnant women and describes clinical management, disease progression, hospital admission, placental abnormalities, and neonatal outcomes.

          open access
          JAMA Netw Open. 2020;3(11):e2029256. doi:10.1001/jamanetworkopen.2020.29256
          Abstract Full Text pdf link PDF
          PHARMACY AND CLINICAL PHARMACOLOGY

          Association Between Low-Dose Aspirin Use and Colorectal Cancer Incidence in Taiwan

          This nested case-control study evaluates the association between duration and recency of low-dose aspirin use and colorectal cancer risk in an East Asian population.

          open access
          JAMA Netw Open. 2020;3(11):e2026494. doi:10.1001/jamanetworkopen.2020.26494
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Evaluation of Adjuvant Treatments for T1 N0 M0 Triple-Negative Breast Cancer

          This cohort study evaluates the association of different adjuvant therapies with survival outcomes in patients with triple-negative breast cancer.

          open access
          JAMA Netw Open. 2020;3(11):e2021881. doi:10.1001/jamanetworkopen.2020.21881
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Machine Learning–Guided Adjuvant Treatment of Head and Neck Cancer

          This cohort study evaluates whether machine learning models could identify patients with intermediate-risk head and neck squamous cell carcinoma who would benefit from chemoradiation.

          open access
          JAMA Netw Open. 2020;3(11):e2025881. doi:10.1001/jamanetworkopen.2020.25881
          Abstract Full Text pdf link PDF
          SURGERY

          Exploration of Factors Associated With Surgeon Deviation From Practice Guidelines for Management of Inguinal Hernias

          This qualitative study explores factors associated with surgeon choice of an open vs minimally invasive approach to inguinal hernia repair to better understand deviations from guidelines.

          open access
          JAMA Netw Open. 2020;3(11):e2023684. doi:10.1001/jamanetworkopen.2020.23684
          Abstract Full Text pdf link PDF
          EMERGENCY MEDICINE

          Delirium in Older Patients With COVID-19 Presenting to the Emergency Department

          This cohort study examines how frequently older adults with coronavirus disease 2019 (COVID-19) present to the emergency department with delirium and their associated hospital outcomes.

          open access
          JAMA Netw Open. 2020;3(11):e2029540. doi:10.1001/jamanetworkopen.2020.29540
          Abstract Full Text pdf link PDF
          CORRECTION

          Errors in Abstract, Results, Discussion, Conclusions, and Table 1

          open access
          JAMA Netw Open. 2020;3(11):e2030492. doi:10.1001/jamanetworkopen.2020.30492
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Effect of Vitamin D3 Supplements on Development of Advanced Cancer: A Secondary Analysis of the VITAL Randomized Clinical Trial

          This secondary analysis of a randomized clinical trial evaluates the effect vitamin D on the incidence of advanced (metastatic or fatal) cancer among adults without cancer at baseline and examines possible effect modification by body mass index.

          open access has audio
          JAMA Netw Open. 2020;3(11):e2025850. doi:10.1001/jamanetworkopen.2020.25850
          Abstract Full Text pdf link PDF
          SUBSTANCE USE AND ADDICTION

          Effect of Pod e-Cigarettes vs Cigarettes on Carcinogen Exposure Among African American and Latinx Smokers: A Randomized Clinical Trial

          This randomized clinical trial examines biomarkers of carcinogen exposure in African American and Latinx smokers who switch to electronic cigarettes vs smoking as usual.

          open access has audio
          JAMA Netw Open. 2020;3(11):e2026324. doi:10.1001/jamanetworkopen.2020.26324
          Abstract Full Text pdf link PDF
          GLOBAL HEALTH

          Predictive Modeling for Perinatal Mortality in Resource-Limited Settings

          This cohort study evaluates the accuracy of a machine learning–based model to predict risk of stillbirth and neonatal mortality in low- and middle-income countries.

          open access
          JAMA Netw Open. 2020;3(11):e2026750. doi:10.1001/jamanetworkopen.2020.26750
          Abstract Full Text pdf link PDF
          CARDIOLOGY

          Variation in Blood Pressure Classification Using 7 Blood Pressure Estimation Protocols Among Adults in Taiwan

          This cross-sectional study examines the intraindividaul discrepancies in blood pressure estimates and classifications based on different BP estimation protocols.

          open access
          JAMA Netw Open. 2020;3(11):e2024311. doi:10.1001/jamanetworkopen.2020.24311
          Abstract Full Text pdf link PDF
          CARDIOLOGY

          Association of Race/Ethnicity-Specific Changes in Antihypertensive Medication Classes Initiated Among Medicare Beneficiaries With the Eighth Joint National Committee Panel Member Report

          This serial cross-sectional study assesses whether any race/ethnicity-specific changes occurred from before to after publication of the Eighth Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure panel member report for the initiation of antihypertensive medication classes in a 5% sample of Medicare beneficiaries aged 66 years or older.

          open access
          JAMA Netw Open. 2020;3(11):e2025127. doi:10.1001/jamanetworkopen.2020.25127
          Abstract Full Text pdf link PDF
          DIABETES AND ENDOCRINOLOGY

          Assessment of Facial Morphologic Features in Patients With Congenital Adrenal Hyperplasia Using Deep Learning

          This cross-sectional study evaluates the use of machine learning for prediction of congenital adrenal hyperplasia based on distinct facial morphologic features.

          open access
          JAMA Netw Open. 2020;3(11):e2022199. doi:10.1001/jamanetworkopen.2020.22199
          Abstract Full Text pdf link PDF
          GASTROENTEROLOGY AND HEPATOLOGY

          Assessment of Incidence of and Surveillance Burden for Hepatocellular Carcinoma Among Patients With Hepatitis C in the Era of Direct-Acting Antiviral Agents

          This decision analytical model study assesses the burden of hepatocellular carcinoma surveillance in the era of new hepatitis C antiviral treatments by projecting the number and the characteristics of new hepatocellular carcinoma incident cases and candidates for routine hepatocellular carcinoma surveillance.

          open access
          JAMA Netw Open. 2020;3(11):e2021173. doi:10.1001/jamanetworkopen.2020.21173
          Abstract Full Text pdf link PDF
          CORRECTION

          Percentage Error in Abstract and Results

          open access
          JAMA Netw Open. 2020;3(11):e2028966. doi:10.1001/jamanetworkopen.2020.28966
          Abstract Full Text pdf link PDF
          CORRECTION

          Errors in Byline, Affiliations, and Conflict of Interest Disclosures

          open access
          JAMA Netw Open. 2020;3(11):e2029176. doi:10.1001/jamanetworkopen.2020.29176
          Abstract Full Text pdf link PDF
          DIABETES AND ENDOCRINOLOGY

          Effects of α-Cyclodextrin on Cholesterol Control and Hydrolyzed Ginseng Extract on Glycemic Control in People With Prediabetes: A Randomized Clinical Trial

          This randomized clinical trial assesses the efficacy of α-cyclodextrin for cholesterol control and that of hydrolyzed ginseng for glycemic control in people with prediabetes and overweight or obesity.

          open access
          JAMA Netw Open. 2020;3(11):e2023491. doi:10.1001/jamanetworkopen.2020.23491
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Evaluation of Fall and Fracture Risk Among Men With Prostate Cancer Treated With Androgen Receptor Inhibitors: A Systematic Review and Meta-analysis

          This systematic review and meta-analysis examines 11 randomized clinical trials to see whether therapy with androgen receptor inhibitors (ARIs), such as enzalutamide, apalutamide, or darolutamide, is associated with an increased risk of falls and fractures in men with prostate cancer.

          open access
          JAMA Netw Open. 2020;3(11):e2025826. doi:10.1001/jamanetworkopen.2020.25826
          Abstract Full Text pdf link PDF
          PUBLIC HEALTH

          Evaluation of a Patient-Centered Fall-Prevention Tool Kit to Reduce Falls and Injuries: A Nonrandomized Controlled Trial

          This nonrandomized controlled trial assesses whether implementation of a nurse-led, patient-centered tool kit for fall prevention was associated with a reduction in rates of falls and fall-related injuries in 3 academic medical centers in Boston and New York City.

          open access
          JAMA Netw Open. 2020;3(11):e2025889. doi:10.1001/jamanetworkopen.2020.25889
          Abstract Full Text pdf link PDF
          INFECTIOUS DISEASES

          Assessment of Risk Factors and Outcomes of Severe Ehrlichiosis Infection

          This cross-sectional study examines risk factors associated with severity of infection in patients with ehrlichiosis.

          open access
          JAMA Netw Open. 2020;3(11):e2025577. doi:10.1001/jamanetworkopen.2020.25577
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Financial Implications of Avapritinib for Treatment of Unresectable Gastrointestinal Stromal Tumors in Patients With a PDGFRA Exon 18 Variant or After 3 Previous Therapies in a Hypothetical US Health Plan

          This economic evaluation assesses the budget impact associated with adding avapritinib for metastatic or unresectable GIST in patients with a platelet-derived growth factor receptor alpha (PDGFRA) exon 18 variant or after 3 or more previous treatments to a hypothetical US health plan formulary.

          open access
          JAMA Netw Open. 2020;3(11):e2025866. doi:10.1001/jamanetworkopen.2020.25866
          Abstract Full Text pdf link PDF
          RESEARCH LETTER PEDIATRICS

          Bidirectional Association Between Daily Physical Activity and Postconcussion Symptoms Among Youth

          This cohort study investigates whether a bidirectional association exists between daily physical activity and postconcussion symptoms among youths with physician-confirmed concussion.

          open access
          JAMA Netw Open. 2020;3(11):e2027486. doi:10.1001/jamanetworkopen.2020.27486
          Abstract Full Text pdf link PDF
          EMERGENCY MEDICINE

          Clinical Effects of Balanced Crystalloids vs Saline in Adults With Diabetic Ketoacidosis: A Subgroup Analysis of Cluster Randomized Clinical Trials

          This subgroup analysis of 2 cluster randomized clinical trials examines adults presenting to the emergency department with diabetic ketoacidosis and determines how long it takes to reach resolution by treating with balanced crystalloids vs saline.

          open access
          JAMA Netw Open. 2020;3(11):e2024596. doi:10.1001/jamanetworkopen.2020.24596
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Patient Adherence to Screening for Lung Cancer in the US: A Systematic Review and Meta-analysis

          This systematic review and meta-analysis examines US lung cancer screening adherence rates, patient characteristics associated with adherence, and diagnostic testing rates after screening.

          open access
          JAMA Netw Open. 2020;3(11):e2025102. doi:10.1001/jamanetworkopen.2020.25102
          Abstract Full Text pdf link PDF
          HEALTH POLICY

          Evaluation of STEMI Regionalization on Access, Treatment, and Outcomes Among Adults Living in Nonminority and Minority Communities

          This cohort study examines the extent to which disparities in access, treatment, and outcomes have changed for patients with ST-segment elevation myocardial infarction (STEMI) who are living in zip codes that are largely composed of Black or Hispanic individuals compared with patients in nonminority communities in regionalized vs nonregionalized counties.

          open access
          JAMA Netw Open. 2020;3(11):e2025874. doi:10.1001/jamanetworkopen.2020.25874
          Abstract Full Text pdf link PDF
          PEDIATRICS

          Characteristics of Pediatric Mild Traumatic Brain Injury and Recovery in a Concussion Clinic Population

          This cohort study examines patient characteristics associated with recovery time in pediatric patients with mild traumatic brain injury treated at concussion specialty clinics.

          open access
          JAMA Netw Open. 2020;3(11):e2021463. doi:10.1001/jamanetworkopen.2020.21463
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Evaluation of Definitive Stereotactic Body Radiotherapy and Outcomes in Adults With Extracranial Oligometastasis

          This case series reports overall progression-free survival, widespread progression outcomes, and prognostic survival factors from a pooled data set of 1033 patients with oligometastasis treated with stereotactic body radiotherapy.

          open access
          JAMA Netw Open. 2020;3(11):e2026312. doi:10.1001/jamanetworkopen.2020.26312
          Abstract Full Text pdf link PDF
          HEALTH POLICY

          Association Between State Medicaid Expansion and Emergency Access to Acute Care Hospitals in the United States

          This cross-sectional study uses hospital-level Medicaid and geospatial data to analyze the association of state expansion of Medicaid under the Patient Protection and Affordable Care Act with emergency access to acute care hospitals.

          open access
          JAMA Netw Open. 2020;3(11):e2025815. doi:10.1001/jamanetworkopen.2020.25815
          Abstract Full Text pdf link PDF
          HEALTH INFORMATICS

          Development and Validation of a Deep Learning Model for Detection of Allergic Reactions Using Safety Event Reports Across Hospitals

          This cross-sectional study describes the development and evaluation of a deep learning model to identify allergic reaction in the free-text narrative of hospital safety reports.

          open access
          JAMA Netw Open. 2020;3(11):e2022836. doi:10.1001/jamanetworkopen.2020.22836
          Abstract Full Text pdf link PDF
          CORRECTION

          Error in the Abstract Results

          open access
          JAMA Netw Open. 2020;3(11):e2029188. doi:10.1001/jamanetworkopen.2020.29188
          Abstract Full Text pdf link PDF
          GERIATRICS

          Association Between Alzheimer Disease and Cancer With Evaluation of Study Biases: A Systematic Review and Meta-analysis

          This systematic review and meta-analysis assesses the likelihood that methodological biases in cohort studies and case-control studies, rather than a common etiology, explain the inverse association between cancer and subsequent Alzheimer disease incidence among older adults.

          open access
          JAMA Netw Open. 2020;3(11):e2025515. doi:10.1001/jamanetworkopen.2020.25515
          Abstract Full Text pdf link PDF
          UROLOGY

          Association of Diet With Erectile Dysfunction Among Men in the Health Professionals Follow-up Study

          This cohort study examines the association of adherence to Mediterranean or Alternative Healthy Eating Index 2010 diets with incidence of erectile dysfunction in men.

          open access
          JAMA Netw Open. 2020;3(11):e2021701. doi:10.1001/jamanetworkopen.2020.21701
          Abstract Full Text pdf link PDF
          HEALTH INFORMATICS

          Use of Deep Learning to Analyze Social Media Discussions About the Human Papillomavirus Vaccine

          This cohort study develops and validates deep learning models to understand public perceptions of human papillomavirus (HPV) vaccines from the perspective of behavior change theories using data from social media.

          open access
          JAMA Netw Open. 2020;3(11):e2022025. doi:10.1001/jamanetworkopen.2020.22025
          Abstract Full Text pdf link PDF
          PSYCHIATRY

          Exposure to Armed Conflict in Childhood vs Older Ages and Subsequent Onset of Major Depressive Disorder

          This cohort study examines the association of age and exposure to neighborhood-level violence with subsequent depression onset in an area with medium-intensity armed conflict.

          open access
          JAMA Netw Open. 2020;3(11):e2019848. doi:10.1001/jamanetworkopen.2020.19848
          Abstract Full Text pdf link PDF
          OBSTETRICS AND GYNECOLOGY

          Maternal Morbidity and Birth Satisfaction After Implementation of a Validated Calculator to Predict Cesarean Delivery During Labor Induction

          This cohort study assesses whether implementation of a validated calculator for likelihood of cesarean delivery at the time of labor induction is associated with maternal morbidity and birth satisfaction.

          open access
          JAMA Netw Open. 2020;3(11):e2025582. doi:10.1001/jamanetworkopen.2020.25582
          Abstract Full Text pdf link PDF
          GERIATRICS

          Assessment of Sensory Impairment and Health Care Satisfaction Among Medicare Beneficiaries

          This cross-sectional study assesses the association between hearing, vision, or dual sensory impairment and patient satisfaction with quality of care, communication from health professionals, and access to care among a nationally representative sample of Medicare beneficiaries.

          open access
          JAMA Netw Open. 2020;3(11):e2025522. doi:10.1001/jamanetworkopen.2020.25522
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Association of Preexisting Interstitial Lung Abnormalities With Immune Checkpoint Inhibitor–Induced Interstitial Lung Disease Among Patients With Nonlung Cancers

          This cohort study evaluates whether interstitial lung abnormalities are associated with immune checkpoint inhibitor–induced interstitial lung disease in patients with nonlung cancers.

          open access
          JAMA Netw Open. 2020;3(11):e2022906. doi:10.1001/jamanetworkopen.2020.22906
          Abstract Full Text pdf link PDF
          PULMONARY MEDICINE

          Association of Electronic Cigarette Use With Incident Respiratory Conditions Among US Adults From 2013 to 2018

          This cohort study examines the association of electronic cigarette use with incidence of respiratory conditions among participants of the Population Assessment of Tobacco and Health Study.

          open access
          JAMA Netw Open. 2020;3(11):e2020816. doi:10.1001/jamanetworkopen.2020.20816
          Abstract Full Text pdf link PDF
          CARDIOLOGY

          Trends, Perioperative Adverse Events, and Survival of Patients With Left Ventricular Assist Devices Undergoing Noncardiac Surgery

          This cohort study examines the trends, patient characteristics, and outcomes associated with noncardiac surgery among patients with left ventricular assist devices (LVADs).

          open access
          JAMA Netw Open. 2020;3(11):e2025118. doi:10.1001/jamanetworkopen.2020.25118
          Abstract Full Text pdf link PDF
          PUBLIC HEALTH

          Estimation of US Children’s Educational Attainment and Years of Life Lost Associated With Primary School Closures During the Coronavirus Disease 2019 Pandemic

          This decision analytical model estimates the potential years of life lost among US primary school–aged children associated with school closures during the coronavirus disease 2019 pandemic.

          open access has active quiz
          JAMA Netw Open. 2020;3(11):e2028786. doi:10.1001/jamanetworkopen.2020.28786
          Abstract Full Text pdf link PDF CME & MOC
          PATHOLOGY AND LABORATORY MEDICINE

          Evaluation of the Use of Combined Artificial Intelligence and Pathologist Assessment to Review and Grade Prostate Biopsies

          This diagnostic study evaluates whether the use of an artificial intelligence–based assistive tool is associated with improvements in the grading of prostate core needle biopsies among general pathologists compared with the majority opinion of subspecialists.

          open access
          JAMA Netw Open. 2020;3(11):e2023267. doi:10.1001/jamanetworkopen.2020.23267
          Abstract Full Text pdf link PDF
          ANESTHESIOLOGY

          Anesthesiologist to Patient Communication: A Systematic Review

          This systematic review studies the literature on communication between patients and anesthesia professionals, with a focus on discussions related to postoperative critical care.

          open access
          JAMA Netw Open. 2020;3(11):e2023503. doi:10.1001/jamanetworkopen.2020.23503
          Abstract Full Text pdf link PDF
          CORRECTION

          Error in Author Affiliation

          open access
          JAMA Netw Open. 2020;3(11):e2029291. doi:10.1001/jamanetworkopen.2020.29291
          Abstract Full Text pdf link PDF
          PUBLIC HEALTH

          Trends in Poor Health Indicators Among Black and Hispanic Middle-aged and Older Adults in the United States, 1999-2018

          This cross-sectional study evaluates which health indicators have improved or worsened among Black and Hispanic middle-aged and older adults since the Minority Health and Health Disparities Research and Education Act of 2000.

          open access
          JAMA Netw Open. 2020;3(11):e2025134. doi:10.1001/jamanetworkopen.2020.25134
          Abstract Full Text pdf link PDF
          EMERGENCY MEDICINE

          Association of Display of Patient Photographs in the Electronic Health Record With Wrong-Patient Order Entry Errors

          This cohort study evaluates whether noninterruptive display of patient photographs in the banner of the electronic health record is associated with a decreased rate of wrong-patient order entry errors.

          open access
          JAMA Netw Open. 2020;3(11):e2019652. doi:10.1001/jamanetworkopen.2020.19652
          Abstract Full Text pdf link PDF
          GASTROENTEROLOGY AND HEPATOLOGY

          Prevalence of Hepatitis B Vaccination Coverage and Serologic Evidence of Immunity Among US-Born Children and Adolescents From 1999 to 2016

          This cross-sectional study used NHANES data from 1999 to 2016 to assess the trends in self-reported hepatitis B vaccination coverage and serologic evidence of immunity among children and adolescents in the US.

          open access
          JAMA Netw Open. 2020;3(11):e2022388. doi:10.1001/jamanetworkopen.2020.22388
          Abstract Full Text pdf link PDF
          NEUROLOGY

          Flying After Concussion and Symptom Recovery in College Athletes and Military Cadets

          This cohort study examines whether there is an association between concussion recovery and airplane travel in college athletes and military cadets.

          open access
          JAMA Netw Open. 2020;3(11):e2025082. doi:10.1001/jamanetworkopen.2020.25082
          Abstract Full Text pdf link PDF
          EMERGENCY MEDICINE

          Association of Affordable Care Act Implementation With Ambulance Utilization for Asthma Emergencies in New York City, 2008-2018

          This quasi-experimental cohort study assesses the association between Affordable Care Act implementation and asthma treatment by examining changes in ambulance dispatch rates for asthma emergencies in New York City between 2008 and 2018.

          open access
          JAMA Netw Open. 2020;3(11):e2025586. doi:10.1001/jamanetworkopen.2020.25586
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Development and Validation of a Risk Model for Breast Cancer–Related Lymphedema

          This prognostic study describes a multivariate linear regression model that combines mammographic breast density with patient, cancer, and treatment factors to identify the possible posttreatment volume of lymphedema in patients with breast cancer.

          open access
          JAMA Netw Open. 2020;3(11):e2024373. doi:10.1001/jamanetworkopen.2020.24373
          Abstract Full Text pdf link PDF
          RESEARCH LETTER ONCOLOGY

          Evaluation of Preoperative Chemotherapy or Radiation and Overall Survival in Patients With Nonmetastatic, Resectable Retroperitoneal Sarcoma

          This cohort study compares overall survival among patients with nonmetastatic, resectable retroperitoneal sarcoma treated with surgical treatment alone vs surgical treatment and chemotherapy or radiation.

          open access
          JAMA Netw Open. 2020;3(11):e2025529. doi:10.1001/jamanetworkopen.2020.25529
          Abstract Full Text pdf link PDF
          EDITORIAL

          An Alternative View of Childhood Blood Pressure Screening: Reframing the Question

          open access has audio
          JAMA Netw Open. 2020;3(11):e2027964. doi:10.1001/jamanetworkopen.2020.27964
          Abstract Full Text pdf link PDF
          PSYCHIATRY

          Effect of Sodium Benzoate vs Placebo Among Individuals With Early Psychosis: A Randomized Clinical Trial

          This randomized clinical trial examines the clinical efficacy of the adjunctive use of sodium benzoate for symptoms in people with early psychosis.

          open access
          JAMA Netw Open. 2020;3(11):e2024335. doi:10.1001/jamanetworkopen.2020.24335
          Abstract Full Text pdf link PDF
          OBSTETRICS AND GYNECOLOGY

          Association of Insurance Status With Provision of Recommended Services During Comprehensive Postpartum Visits

          This cross-sectional study examines rates of recommended services during comprehensive postpartum visits and differences between Medicaid and non-Medicaid insurance type among US women.

          open access
          JAMA Netw Open. 2020;3(11):e2025095. doi:10.1001/jamanetworkopen.2020.25095
          Abstract Full Text pdf link PDF
          NEUROLOGY

          Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Intellectual Disability and Delayed Childhood Milestones

          This cohort study evaluates risk of intellectual disability and delayed childhood milestones among children exposed prenatally to valproate and other antiepileptic drugs.

          open access
          JAMA Netw Open. 2020;3(11):e2025570. doi:10.1001/jamanetworkopen.2020.25570
          Abstract Full Text pdf link PDF
          HEALTH POLICY

          Clinical Trial Evidence Supporting US Food and Drug Administration Approval of Novel Cancer Therapies Between 2000 and 2016

          This comparative effectiveness research examines clinical trial data on treatment outcomes used to support US Food and Drug Administration approval of novel cancer therapies that were approved for the first time between 2000 and 2016.

          open access
          JAMA Netw Open. 2020;3(11):e2024406. doi:10.1001/jamanetworkopen.2020.24406
          Abstract Full Text pdf link PDF
          RESEARCH LETTER PUBLIC HEALTH

          Association Between Health Care Utilization and Immigration Enforcement Events in San Francisco

          This cohort study explores whether an inclusive, local health care system could serve as a buffer against adverse effects on access to health care due to actions related to immigration status in patients who are likely undocumented.

          open access
          JAMA Netw Open. 2020;3(11):e2025065. doi:10.1001/jamanetworkopen.2020.25065
          Abstract Full Text pdf link PDF
          RESEARCH LETTER DERMATOLOGY

          Use of Skin Cancer Procedures, Medicare Reimbursement, and Overall Expenditures, 2012-2017

          This cohort study describes recent trends in use and payment rates and in overall expenditure for skin cancer procedures in the Medicare Part B population in the United States.

          open access
          JAMA Netw Open. 2020;3(11):e2025139. doi:10.1001/jamanetworkopen.2020.25139
          Abstract Full Text pdf link PDF
          CORRECTION

          Errors in Byline and Affiliations

          open access
          JAMA Netw Open. 2020;3(11):e2029182. doi:10.1001/jamanetworkopen.2020.29182
          Abstract Full Text pdf link PDF
          HEALTH POLICY

          Association of Racial/Ethnic and Gender Concordance Between Patients and Physicians With Patient Experience Ratings

          This cross-sectional study evaluates the associations between the patient experience as measured by scores on the Press Ganey Outpatient Medical Practice Survey and patient-physician racial/ethnic and gender concordance.

          open access
          JAMA Netw Open. 2020;3(11):e2024583. doi:10.1001/jamanetworkopen.2020.24583
          Abstract Full Text pdf link PDF
          HEALTH POLICY

          Association of Highly Restrictive State Abortion Policies With Abortion Rates, 2000-2014

          This cohort study evaluates the association of restrictive abortion laws in 18 states with state abortion rates.

          open access
          JAMA Netw Open. 2020;3(11):e2024610. doi:10.1001/jamanetworkopen.2020.24610
          Abstract Full Text pdf link PDF
          DIABETES AND ENDOCRINOLOGY

          Prevalence of Gestational Diabetes in India by Individual Socioeconomic, Demographic, and Clinical Factors

          This cross-sectional study provides a comprehensive national assessment of gestational diabetes in India and its socioeconomic, demographic, and geographic associations.

          open access
          JAMA Netw Open. 2020;3(11):e2025074. doi:10.1001/jamanetworkopen.2020.25074
          Abstract Full Text pdf link PDF
          OBSTETRICS AND GYNECOLOGY

          Development of a Dynamic Diagnosis Grading System for Infertility Using Machine Learning

          This prognostic study assesses whether machine learning can be used to develop a dynamic scoring system for predicting the severity of infertility in patients.

          open access
          JAMA Netw Open. 2020;3(11):e2023654. doi:10.1001/jamanetworkopen.2020.23654
          Abstract Full Text pdf link PDF
          PSYCHIATRY

          Incidence, Persistence, and Remission Rates of Insomnia Over 5 Years

          This cohort study assess the incidence, persistence, and remission rates of insomnia over a 5-year period in a population-based sample in Canada.

          open access
          JAMA Netw Open. 2020;3(11):e2018782. doi:10.1001/jamanetworkopen.2020.18782
          Abstract Full Text pdf link PDF
          HEALTH POLICY

          Trends in Birth Rates After Elimination of Cost Sharing for Contraception by the Patient Protection and Affordable Care Act

          This cross-sectional study assesses the association of the elimination of cost sharing for contraception under the Patient and Protection and Affordable Care Act (ACA) with birth rates by income level among commercially insured women.

          open access
          JAMA Netw Open. 2020;3(11):e2024398. doi:10.1001/jamanetworkopen.2020.24398
          Abstract Full Text pdf link PDF
          INFECTIOUS DISEASES

          Association of Adverse Neighborhood Exposures With HIV Viral Load in Pregnant Women at Delivery

          This cohort study evaluates the association between adverse neighborhood exposures and virologic control in pregnant women with HIV at labor and delivery.

          open access
          JAMA Netw Open. 2020;3(11):e2024577. doi:10.1001/jamanetworkopen.2020.24577
          Abstract Full Text pdf link PDF
          PULMONARY MEDICINE

          Clinical, Bronchoscopic, and Imaging Findings of e-Cigarette, or Vaping, Product Use–Associated Lung Injury Among Patients Treated at an Academic Medical Center

          This case series describes the clinical features, bronchoscopic findings, imaging patterns, and outcomes of e-cigarette, or vaping, product use–associated lung injury (EVALI).

          open access
          JAMA Netw Open. 2020;3(11):e2019176. doi:10.1001/jamanetworkopen.2020.19176
          Abstract Full Text pdf link PDF
          HEALTH POLICY

          US Clinicians’ Experiences and Perspectives on Resource Limitation and Patient Care During the COVID-19 Pandemic

          This qualitative study describes the perspectives and experiences of clinicians involved in institutional planning for resource limitation and/or patient care during the coronavirus disease 2019 (COVID-19) pandemic.

          open access has active quiz
          JAMA Netw Open. 2020;3(11):e2027315. doi:10.1001/jamanetworkopen.2020.27315
          Abstract Full Text pdf link PDF CME & MOC
          HEALTH POLICY

          Changes in Health Services Use Among Commercially Insured US Populations During the COVID-19 Pandemic

          This cross-sectional study analyzes health insurance claims among commercially-insured individuals to asess changes in the use of health services in the Unted States during the initial phase of the COVID-19 pandemic.

          open access has active quiz
          JAMA Netw Open. 2020;3(11):e2024984. doi:10.1001/jamanetworkopen.2020.24984
          Abstract Full Text pdf link PDF CME & MOC
          EDITORIAL

          Elective Care and Health Services Research in the COVID-19 Era

          open access has active quiz
          JAMA Netw Open. 2020;3(11):e2025731. doi:10.1001/jamanetworkopen.2020.25731
          Abstract Full Text pdf link PDF CME & MOC
          PUBLIC HEALTH

          Evaluation of Trust Within a Community After Survivor Relocation Following the Great East Japan Earthquake and Tsunami

          This cohort study examined levels of community trust in survey responses from communities in Iwanuma City, Japan, hosting resettled survivors of the 2011 Great East Japan Earthquake and Tsunami.

          open access
          JAMA Netw Open. 2020;3(11):e2021166. doi:10.1001/jamanetworkopen.2020.21166
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Trends in Positive BRCA Test Results Among Older Women in the United States, 2008-2018

          This cross-sectional study assesses whether the rate of positive BRCA test results changed between 2008 and 2018 among older women in the United States.

          open access
          JAMA Netw Open. 2020;3(11):e2024358. doi:10.1001/jamanetworkopen.2020.24358
          Abstract Full Text pdf link PDF
          HEALTH POLICY

          Medicaid Expansion and Mortality Among Patients With Breast, Lung, and Colorectal Cancer

          This cross-sectional study examines whether Medicaid expansion is associated with improved mortality among patients with breast, colorectal, and lung cancer.

          open access
          JAMA Netw Open. 2020;3(11):e2024366. doi:10.1001/jamanetworkopen.2020.24366
          Abstract Full Text pdf link PDF
          ENVIRONMENTAL HEALTH

          Evaluation of Secondhand Smoke Exposure in New York City Public Housing After Implementation of the 2018 Federal Smoke-Free Housing Policy

          This cohort study examines whether the 2018 implementation of a federal ban on smoking in public housing settings was associated with a decrease in indoor levels of secondhand smoke in New York City (NYC) public housing developments 12 months later.

          open access
          JAMA Netw Open. 2020;3(11):e2024385. doi:10.1001/jamanetworkopen.2020.24385
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Association of Addition of Ablative Therapy Following Transarterial Chemoembolization With Survival Rates in Patients With Hepatocellular Carcinoma

          This cohort study examined the association of adding ablative therapy to transarterial chemoembolization with overall survival and freedom from local progression among patients with hepatocellular carcinoma (HCC).

          open access
          JAMA Netw Open. 2020;3(11):e2023942. doi:10.1001/jamanetworkopen.2020.23942
          Abstract Full Text pdf link PDF
          NEUROLOGY

          Association of Serum Neurofilament Light Levels With Long-term Brain Atrophy in Patients With a First Multiple Sclerosis Episode

          This cohort study examines the association of neurofilament light levels with long-term brain atrophy and disease progression in multiple sclerosis.

          open access
          JAMA Netw Open. 2020;3(11):e2016278. doi:10.1001/jamanetworkopen.2020.16278
          Abstract Full Text pdf link PDF
          PUBLIC HEALTH

          Association of Changes in Missouri Firearm Laws With Adolescent and Young Adult Suicides by Firearms

          This cross-sectional study examines changes in firearm suicide rates in Missouri following the loosening of state firearm restrictions by comparing reported suicide rates with states with similar demographic characteristics that did not change firearm laws.

          open access
          JAMA Netw Open. 2020;3(11):e2024303. doi:10.1001/jamanetworkopen.2020.24303
          Abstract Full Text pdf link PDF
          ENVIRONMENTAL HEALTH

          Association of Neighborhood Deprivation With Epigenetic Aging Using 4 Clock Metrics

          This cross-sectional study examines the association between neighborhood deprivation and estimates of epigenetic age acceleration and genome-wide methylation among women in the US and Puerto Rico.

          open access
          JAMA Netw Open. 2020;3(11):e2024329. doi:10.1001/jamanetworkopen.2020.24329
          Abstract Full Text pdf link PDF
          SUBSTANCE USE AND ADDICTION

          Modeling Mitigation Strategies to Reduce Opioid-Related Morbidity and Mortality in the US

          This decision analytical model estimates the future burden of opioid-related morbidity and mortality in the US from 2020 to 2029 and examines strategies that may be associated with mitigation of the opioid epidemic.

          open access
          JAMA Netw Open. 2020;3(11):e2023677. doi:10.1001/jamanetworkopen.2020.23677
          Abstract Full Text pdf link PDF
          SURGERY

          Evaluation of Outcomes Following Surgery for Locally Advanced Pancreatic Neuroendocrine Tumors

          This case series examines data from 2003 to 2018 regarding patients who underwent aggressive resection operative treatment for locally advanced pancreatic neuroendocrine tumors and their outcomes in terms of disease recurrence, quality of life, and overall 5-year survival.

          open access
          JAMA Netw Open. 2020;3(11):e2024318. doi:10.1001/jamanetworkopen.2020.24318
          Abstract Full Text pdf link PDF
          SURGERY

          Association Between Cardiac Surgeons’ Number of Years in Practice and Surgical Outcomes in New York Cardiac Centers

          This cross-sectional study uses surgeon-level outcomes data from the 2014-2016 New York State Cardiac Data Reporting System to assesses the association between surgeons’ number of years in practice and outcomes in cardiac surgery.

          open access
          JAMA Netw Open. 2020;3(11):e2023671. doi:10.1001/jamanetworkopen.2020.23671
          Abstract Full Text pdf link PDF
          ONCOLOGY

          Evaluation of a Low-Dose Computed Tomography Lung Cancer Screening Program in Henan, China

          This cross-sectional study assesses the participation and detection rates of a lung cancer screening program in China and the factors associated with participation and detection among individuals at high risk for lung cancer.

          open access
          JAMA Netw Open. 2020;3(11):e2019039. doi:10.1001/jamanetworkopen.2020.19039
          Abstract Full Text pdf link PDF
          PEDIATRICS

          Association of Maternal Prepregnancy Body Mass Index With Fetal Growth and Neonatal Thalamic Brain Connectivity Among Adolescent and Young Women

          This cohort study examines the association of prepregnancy BMI with fetal growth development and functional connectivity outcomes among adolescent and young women.

          open access
          JAMA Netw Open. 2020;3(11):e2024661. doi:10.1001/jamanetworkopen.2020.24661
          Abstract Full Text pdf link PDF
          PEDIATRICS

          Assessment of Neighborhood Poverty, Cognitive Function, and Prefrontal and Hippocampal Volumes in Children

          This cross-sectional study evaluates whether neighborhood poverty is associated with cognitive function and prefrontal and hippocampal brain structure in ways that are dissociable from household socioeconomic status.

          open access
          JAMA Netw Open. 2020;3(11):e2023774. doi:10.1001/jamanetworkopen.2020.23774
          Abstract Full Text pdf link PDF
          GASTROENTEROLOGY AND HEPATOLOGY

          Development, Validation, and Evaluation of a Simple Machine Learning Model to Predict Cirrhosis Mortality

          This cohort study compares different machine learning methods in predicting overall mortality in cirrhosis and uses machine learning to select easily scored clinical variables for a novel prognostic model in patients with cirrhosis.

          open access
          JAMA Netw Open. 2020;3(11):e2023780. doi:10.1001/jamanetworkopen.2020.23780
          Abstract Full Text pdf link PDF
          RESEARCH LETTER SURGERY

          Diagnosis of Thoracic Aortic Aneurysms by Computed Tomography Without Allometric Scaling

          This diagnostic study of computed tomography scans at a single tertiary care center compares radiologist descriptions of abnormal size ascending aortas with definitions of aorta diameters defined by nomograms.

          open access
          JAMA Netw Open. 2020;3(11):e2023689. doi:10.1001/jamanetworkopen.2020.23689
          Abstract Full Text pdf link PDF
          HEMATOLOGY

          The Efficacy and Safety of Vitamin C for Iron Supplementation in Adult Patients With Iron Deficiency Anemia: A Randomized Clinical Trial

          This randomized clinical trial compares the equivalence and assesses the safety of oral iron supplements plus vitamin C vs oral iron supplements alone among patients with iron deficiency anemia.

          open access
          JAMA Netw Open. 2020;3(11):e2023644. doi:10.1001/jamanetworkopen.2020.23644
          Abstract Full Text pdf link PDF
          MEDICAL EDUCATION

          Trends in Race/Ethnicity Among Applicants and Matriculants to US Surgical Specialties, 2010-2018

          This cross-sectional study assesses trends in the percentage of applicants and matriculants to US surgical specialties who identified as part of a racial/ethnic group underrepresented in medicine from the 2010-2011 to 2018-2019 academic years

          open access
          JAMA Netw Open. 2020;3(11):e2023509. doi:10.1001/jamanetworkopen.2020.23509
          Abstract Full Text pdf link PDF
          CARDIOLOGY

          Characteristics Associated With High-Performing Pediatric Heart Transplant Centers in the United States From 2006 to 2015

          This cohort study examines characteristics of high-performing pediatric heart transplant centers in the United States.

          open access
          JAMA Netw Open. 2020;3(11):e2023515. doi:10.1001/jamanetworkopen.2020.23515
          Abstract Full Text pdf link PDF
          NEPHROLOGY

          Association of Chronic Condition Special Needs Plan With Hospitalization and Mortality Among Patients With End-Stage Kidney Disease

          This cohort study examines whether enrollment in a chronic condition special needs plan is associated with improved clinical outcomes and quality of life among patients with end-stage kidney disease (ESKD).

          open access
          JAMA Netw Open. 2020;3(11):e2023663. doi:10.1001/jamanetworkopen.2020.23663
          Abstract Full Text pdf link PDF
          HEALTH INFORMATICS

          Development and Performance of a Clinical Decision Support Tool to Inform Resource Utilization for Elective Operations

          In this prognostic study, the development and performance of a clinical decision support tool to inform resource utilization for elective procedures requiring inpatient care were evaluated.

          open access
          JAMA Netw Open. 2020;3(11):e2023547. doi:10.1001/jamanetworkopen.2020.23547
          Abstract Full Text pdf link PDF
          JAMA Network Open Masthead

          JAMA Network Open

          open access
          JAMA Netw Open. 2020;3(11):e2025663. doi:10.1001/jamanetworkopen.2020.25663
          Abstract Full Text
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