New Online

This randomized clinical trial examines intervention to promote self-care in patients with acute heart failure who are discharged from the emergency department.

This secondary cohort study evaluates the associations of visit-to-visit variability in indexes of kidney function and serum electrolytes with the risk of adverse clinical outcomes among patients with chronic, stable heart failure with preserved ejection fraction.

This cohort study assesses associations of carotid artery magnetic resonance imaging plaque characteristics with incident cardiovascular disease events.

This Patient Page describes different types of pacemakers and other considerations for patients who need a pacemaker.

This registry-based study compares out-of-hospital cardiac arrest outcomes in the first few weeks of the coronavirus disease 2019 pandemic in 2020 with outcomes in the same period in 2019.

This post hoc analysis of data from the Systolic Blood Pressure Intervention Trial determines the association between the proportion of West African ancestry with response to antihypertensive medication, blood pressure control, kidney function, and risk of adverse cardiovascular events among self-identified Black individuals.

This cohort study evaluates candidacy for initiation of dapagliflozin based on the US Food and Drug Administration label among contemporary US patients with heart failure with reduced ejection fraction and describes potential barriers to therapeutic optimizations.

This secondary exploratory analysis evaluates the association between baseline low-density lipoprotein cholesterol and the percentage low-density lipoprotein cholesterol reduction with a statin, ezetemibe, and a PCSK9 inhibitor using data from 3 randomized clinical trials

This cohort study investigates the association of early-life trauma with adverse events and examines whether inflammation plays a role.

This secondary analysis the Vericiguat Global Study in Subjects With Heart Failure With Reduced Ejection Fraction clinical trial evaluates clinical characteristics, outcomes, and treatment response to vericiguat according to prespecified index event subgroups and time from index heart failure hospitalization.

This cross-sectional study assesses the concordance between Pooled Cohort Equations to Prevent Heart Failure risk scoring and the presence of subclinical cardiac maladaptation in the community.

A 40-year-old woman with a history of vitral valve endocarditis is pregnant and presents with mild exertional dyspnea, a right ventricular heave, and elevated jugular venous pulsation. What would you do next?

This cohort study assesses whether left ventricular volumes and volume-derived left ventricular ejection fraction are determinants of mortality in aortic regurgitation.

This meta-analysis of 7 population-based cohort studies assesses the association between circulating monocyte-chemoattractant protein–1 levels and risk of cardiovascular disease and death.

This cohort study describes temporal trends and institutional variations of multivessel percutaneous coronary intervention use for ST-elevation myocardial infarction in the United States between 2009 and 2018.

This study investigates associations of the lifelong genetic inhibition of PCSK9 with plasma liver enzymes and nonalcoholic fatty liver disease by using the loss-of-function variant PCSK9-p.Arg46Leu as a genetic instrument.

A 27-year-old woman with a history of heroin use presented with syncope but denied chest pain, shortness of breath, palpitations, or recent illicit drug use. Results of imaging tests were unremarkable, and electrocardiography was ordered. What would you do next?