Explore the latest in diabetes, including advances in screening, prevention, diagnosis, and treatment of the disease.
This Medical Letter compares a newly approved fixed-dose combination pill comprising the sodium-glucose cotransporter 2 inhibitor empagliflozin, the dipeptidyl peptidase-4 inhibitor linagliptin, and extended-release metformin, with available formulations of each of the pill’s individual components for oral treatment of type 2 diabetes in adults.
A 63-year-old woman with type 2 diabetes was referred for refractory hypomagnesemia (1.4 mg/dL; low normal, 1.8 mg/dL). Her medications included liraglutide, metformin, lisinopril, and magnesium oxide (400 mg twice daily). A recent hemoglobin A1c level was 10.8%, and her urinary magnesium was 117 mg. How do you interpret the urine level, and what would you do next?
This cohort study examines the mechanisms, risk factors, and outcomes associated with acute kidney injury during pediatric diabetic ketoacidosis.
This study examines cost sharing for novel second-line diabetes treatment agents under Medicare Part D.
This cross-sectional study evaluates the association of the distribution of diabetic retinopathy lesions with optical coherence tomography angiography (OCTA) metrics and the severity of diabetic retinopathy.
This cohort study evaluates the association of heart failure and ischemic heart disease with diabetes complications.
This ancillary study of a randomized clinical trial examines the long-term associations of an intensive lifestyle intervention for type 2 diabetes with health care use, spending, and disability.
This cohort study characterizes the relative association of conventional and novel biomarkers in Mediterranean diet–related type 2 diabetes risk reduction in a US population.
This randomized clinical trial assesses the efficacy of α-cyclodextrin for cholesterol control and that of hydrolyzed ginseng for glycemic control in people with prediabetes and overweight or obesity.
This subgroup analysis of 2 cluster randomized clinical trials examines adults presenting to the emergency department with diabetic ketoacidosis and determines how long it takes to reach resolution by treating with balanced crystalloids vs saline.
This cohort study evaluates candidacy for initiation of dapagliflozin based on the US Food and Drug Administration label among contemporary US patients with heart failure with reduced ejection fraction and describes potential barriers to therapeutic optimizations.
This cross-sectional study evaluates which health indicators have improved or worsened among Black and Hispanic middle-aged and older adults since the Minority Health and Health Disparities Research and Education Act of 2000.
This case report describes an adolescent male with a history of prediabetes and obesity who presented with a diagnosis of confluent and reticulated papillomatosis with features of acanthosis nigricans.
This cross-sectional study provides a comprehensive national assessment of gestational diabetes in India and its socioeconomic, demographic, and geographic associations.
This cluster randomized trial compares the effects of an online weight management program with vs without a health manager monitoring progress vs usual care on 12-month weight change among adults with overweight or obesity and a diagnosis of hypertension or type 2 diabetes.
This randomized clinical trial examines the effect of a group-based lifestyle intervention with or without trained volunteers with type 2 diabetes on the risk of progression to type 2 diabetes in British populations with a high-risk glycemic category.
This national cohort study evaluates trends in heart failure incidence across risk factor strata, including hypertension, diabetes, obesity, acute myocardial infarction, and atrial fibrillation among Medicare beneficiaries.
This combination evidence-based and consensus clinical guideline presents recommendations and statements of good practice for the medical care of adults with Down syndrome, including screening, diagnosis, and treatment of behavioral health conditions, dementia, diabetes, cardiovascular disease, obesity, osteoporosis, atlantoaxial instability, hypothyroidism, and celiac disease.
This cross-sectional study assesses drug coverage, formulary restrictions, median retail prices, and annual out-of-pocket costs associated with commonly used insulin products across Medicare Part D plans.
This cross-sectional study estimates the prevalence of hypertension and diabetes with biological measures and evaluates access to care among Syrian refugees in northern Jordan.
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